Category: News

Dr. Isabelle Ragueneau-Majlessi, Clinical Professor and Director of the DIDB Program, is an invited speaker at the session entitled “Overcoming potential setbacks? Prediction of Drug-Drug interactions via Computational Modeling“, taking place on Wednesday November 5th (7:00-8:30am) at the AAPS Meeting in San Diego. She will be presenting on “Indexing and Curating Drug-Drug Interaction Data: experience of the University of Washington Drug Interaction Database”.

Please visit the DIDB Team at Booth #408 during this year’s ISSX/JSSX Meeting to be held in San Francisco October 19 -23, 2014.

Also, please come to the following poster presentations:

• P94 – ASSESSMENT OF THE IMPACT OF RENAL OR HEPATIC IMPAIRMENT VS PHARMACOLOGIC INHIBTION ON SYSTEMIC EXPOSURE OF DRUGS (Cathy Yeung, Makiko Kusama, Huixia Zhang, Isabelle Ragueneau-Majlessi, Sophie Argon, Li Li, Peter Chang, Ping Zhao, Lei Zhang, Kenta Yoshida, Issam Zineh, Yuichi Sugiyama, Shiew-Mei Huang).
• Monday October 20
• Presented by Authors: 1:15 – 2:00 pm  (Dr. Cathy Yeung)

• P173 – DRUG DISPOSITION AND DRUG-DRUG INTERACTION DATA IN 2013 FDA NEW DRUG APPLICATIONS: A SYSTEMATIC REVIEW (Jingjing Yu and Isabelle Ragueneau-Majlessi).
• Monday October 20
• Presented by Authors: 4:30-5:15 pm (Dr. Jingjing Yu)

• P390 – USE OF IN VIVO DISPOSITION DATA TO DETERMINE CYP2D6 PROBE fm VALUES AND DEVELOP PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELS TO PREDICT GENOTYPE DEPENDENT CYP2D6-MEDIATED DRUG-DRUG INTERACTIONS (Mariko Nakano, Jingjing Yu, Sophie Argon, Isabelle Ragueneau-Majlessi, Nina Isoherranen).
• Tuesday October 21
• Presented by Authors: 6:15-7:00 pm (Dr. Mariko Nakano)

Check out the new DIDB at https://didb.druginteractionsolutions.org

What’s new?

• Whole new look and feel, but don’t get worried, the workflow remains unchanged. You’ll be able to jump right in.
• New improved autocompletes to find the compound or therapeutic class you want.
• You can now select a default compound to use in all DIDB queries.
• New sortable and searchable query result tables.  Give these a try, you’ll like them.
• Oh, and this all works on your tablet or phone… well, if your phone is shiny and new.

If a picture is worth a thousand words, a fully functioning website is worth a thousand pictures. Check it out https://didb.druginteractionsolutions.org.

This new version of DIDB went live on November 3rd.

If you have any questions or comments please contact us.

Please visit the DIDB Team at Booth #602 during this year’s 10th International ISSX Meeting to be held in Toronto, Canada September 29 – October 3, 2013.

Also, please come to the following poster presentation:

• P168 – Analysis of metabolism and transport drug interaction data in new drug applications approved in 2012 (Mulgaonkar A, Ragueneau-Majlessi I, Chung S, Zhang L, and Zhao P)
• Tuesday, October 1
• Poster Viewing: 10:30 – 14:00
• Presented by Authors: 13:30 – 14:00 (Dr. Ragueneau-Majlessi)

Dr. Nina Isoherannen, Associate Professor in Pharmaceutics, will become a part-time scientific contributor for the Drug Interaction Database program as of July 1^st, 2013.

The DIDB platform will be upgraded this week-end to run with the latest version of its software. If you experience any issue, please contact us.

A new gene summary for CYP3A4 gene polymorphism is available in the Summaries section of e-PKGene. As usual, comments and suggestions are welcome!

The DIDB program has released its pharmacogenetic database, e-PKGene. For more information on e-PKgene please see the e-PKGene User Guide.

Part of the release also includes a new website where DIDB users can easily access both applications with a single login.

First, you need to register and create an individual account. To do so, use your current company login/password for the DIDB, and follow the few steps. When asked to provide your email address, please provide your WORK email.

If you have any questions regarding the release or experience any difficulty creating your new password, please contact us.