An Evidence-based Approach for Managing DDI risk for Patients in Clinical Trials

Presented at the 127th ASCPT International Meeting, March 2026
Katie Owens, Jingjing Yu, Chris Kinsella, Sophie Argon, and Isabelle Ragueneau-Majlessi

2026 ASCPT Poster Presentation – ConmedsDDI

Abstract

A systematic evidence-based approach leveraging regulatory approved characterizations per the ICH M12 Guideline for Drug Interaction Studies and clinical DDI and/or pharmacogenetic data can be used to generate dynamic lists of potential concomitant medications for use in a particular clinical trial.